Professor of Medical Microbiology at the University of Uppsala, Sweden (http://www.uu.se).
PhD (VMD) in Veterinary Microbiology (specialized in Bacteriology) at the Swedish University of Agricultural Sciences,
Uppsala, Sweden (http://www.bvf.slu.se).
training (cell-cell adhesion) at the Swedish University of Agricultural Sciences, Uppsala, Sweden (http://www.bvf.slu.se).
1983- DVM (Doctor of Veterinary Medicine) with MVSc (Master of Veterinary Sciences)
at the Kharkov State Veterinary Academy, Ukraine (http://zoovet.kharkov.ua/eng/index.htm).
1983- Professional Russian language at the Kharkov State Veterinary Academy, Ukraine (http://zoovet.kharkov.ua/eng/index.htm).
Life Science, at Addis Ababa University, Ethiopia (http://www.aau.edu.et).
1974- Secondary School
education at Jimma Miazia 27 Comprehensive Secondary School, Ethiopia (http://miaziaalumni.tripod.com/id11.html).
2004 - present: Associate
Principal NeuroScientist at the global Drug Discovery Division, Preclinical Research & Development (R & D), at the
AstraZeneca Södertälje, Sweden (http://www.astrazeneca.com).
1998 - present: Monitoring Scientist (Animal welfare inspection) of pre-clinical studies on international CROs.
1998 - 2004: Head of Transgenics at the AstraZeneca Pharmaceuticals
Plc, Preclinical R & D, Södertälje, Sweden.
1996 - 1997: Deputy
Director of the Department of Veterinary Services, at Astra Arcus Pharmaceuticals Plc, R & D Södertälje, Sweden.
1994 - 1996: Preclinical
Study Director on the development of drug against Multiple Sclerosis at Astra Arcus. Pharmaceuticals Plc, R &
D, Södertälje, Sweden.
1993 - 1994: Preclinical
Study Director on the development of drug against human gastritis at Astra Arcus Pharmaceuticals Plc, R & D, Södertälje,
1991 - 1993: Scientific
consultant and project leader on a vaccine trial project for Alfa Laval Agri International, at SLU, Uppsala, Sweden.
1986 - 1991: Research Associate
at the Department of Veterinary Microbiology at the Swedish University of Agricultural Sciences (SLU), Uppsala, Sweden.
1984: District Veterinary Surgeon in a mixed veterinary practice in Kharkov, Ukraine.
1983 – 1984: Laboratory
Veterinarian, at Valky Regional Veterinary Diagnostic Laboratory, Ukraine.
1993 – present: Periodic
lecturing Microbiology (mainly Bacteriology) to medical and Bio-Medical undergraduate students, to veterinary students
1983 - 1984: Teaching/training
veterinarians on different laboratory diagnostic methods
· Wide experience (over 20 years)
working with microbes and microbial (bacterial/viral) infections in the clinics and laboratory.
· Vaccine (recombinant vaccines)
against staphylococcal and streptococcal infections, construction, immunization (vaccination), challenge and evaluation of
toxicity and efficacy.
· Neuropathology: Alzheimer, Stroke,
· Dementia (age-related), cognitive
impairment, behaviours analysis
· Fertility: In vitro fertilization
(IVF) in mice model.
Low temperature studies of biological systems
· Manipulation of pre-implantation
embryo and germ cells.
· DNA analysis (genotyping) by PCR
· Leading research projects dealing
with intra-mammary infections.
· Scientific supervision of researchers,
graduate students, visiting scientists and research veterinarians working on the pathogenesis of bacterial infections.
· Coordinating and management of
pre-clinical studies globally at international CROs.
· Non-clinical safety studies, OEDC,
GLP principles & FDA and GLP regulations.
of a “Methodology to identify therapeutically active compounds” in preclinical studies. Patent internationally
a novel surface antigen a “vaccine candidate antigen” on S.aureus causing intra-mammary infections.
· Range ecology management
and livestock production
· Experimental animals management,
experimentation in target discovery and validation; Ethics and animal experiments
· Genetics and advanced functional
· Genetically modified (Transgenic)
· Drug toxicity and efficacy evaluation
· Non-clinical safety studies
· Embryology; embryo transfer; Cryopreservation
(low temperature biology) of embryos
· Human cells and cell culturing
· Statistics in biomedical research
· Women empowerment and gender issues
· Ethic & animal experimentation
in pharmaceutical industries.
Participations on Scientific Conferences and Workshops
I was invited and presented research papers and other development associated reports on numerous international
conferences, congresses, and workshops. I also organized and chaired international workshops on urban development initiatives.
Invited presentations, selected (since 1992)
International Symposium on Staphylococci and Staphyloccal Infections. Stockholm, Sweden, 29 June-3 July 1992.
· VIII-th International Workshop on Immunodeficient Animals. Utrecht, Netherlands,
July 3-7, 1994.
· XIII-th International Conference on Ethiopia Studies, Kyoto, Japan, Dec., 12-17 1997.
· International Conference on the use of humane endpoints in animal experiments for biomedical research, Zeist, The
Netherlands, Nov, 22-25, 1998.
· First International Conference on AIDS in Ethiopia: Fighting for life, Addis Ababa, Ethiopia, Nov 7-10, 1999.
· Behavioural phenotyping of mouse mutants, Cologne, Germany, Feb. 17-19, 2000.
· Annual Meeting
on Bacterial Adhesion. Uppsala, Sweden, January 26, 1991.
on Advanced Wound Care/Medical Research Forum on Wound Repair. New Orleans, U.S.A., Apr., 23-25, 1992.
International Congress of Immunology: Transmembrane signalling in the immune system, Debrecen, Hungary, Aug., 18-22, 1992.
International Congress of Immunology. Budapest, Hungary, August 23-28, 1992.
III-rd International Mastitis Seminar, Tel-Aviv, Israel, May 28-June 1, 1995. Vaccine for the Year 200. Gothenburg, Sweden,
Oct., 26-27, 1994.
International Symposium on Staphylococci and Staphylococcal Infections. Aix-Les-Bains, France, June 23-26, 1996.
Joint Meeting, XII General Assembly & Conference, 7th FELASA Symposium, Palma de Mallorca, Balearic Islands, Spain, May,
Annual Symposium and Educational days of the Scandinavian Society for Laboratory Animal Science, Djurönäset, Stockholm, Sweden,
May 4-7, 2000
· 51-th AALAS
National meeting, San Diego, USA, Nov, 9-11, 2000
Board and Board of Directors
· Editorial Board: International Advisory Editorial of The Horn of Africa Journal of AIDS
(HAJA). HAJA publishes peer-reviewed articles on all aspects of neurological disease and HIV/AIDS.
· Board of Directors: Board
of Directors in The African AIDS Initiative International AAII, an international
NGO dedicated to promoting HIV/AIDS awareness in Africa.
· Advisory Board: The Science Advisory Board, (www.scienceboard.net).
Experiences/Contributions in Urban Community Health Development
Identification of community health problems in the poorest suburbs of Addis Ababa, Ethiopia and analysis of community
needs through feasibility studies (pilot programs).
Assessment of the problem, project and program development
& preparation of proposals for funding, effective and sustainable program development and developing monitoring and effectiveness
Assist emerging/existing non-profit program/projects that
their efforts meet community needs, mission and vision statement development, community outreach and promotional campaigns.
Support urban development projects interpreting urban development policies and programs to the local people.
Program/project and evaluation: establishing appropriate monitoring
and evaluation systems that provide the basis for improving, establishing integrated monitoring and evaluation systems for
continuous and periodic assessment of progress at all levels during the program/project period, evaluating the impact, effectiveness
and cost-effectiveness of the project interventions.
Program/project results reporting on international & national
conferences & workshops.
· Project appraisal & Co-coordinating
a trilateral (Sida/AEHPS/CBISDO) project on the prevention of HIV/AIDS pandemic in Ethiopia. (Sida= the Swedish International
Development Agency in Sweden).
of results and reports on HIV/AIDS prevention
and associated efforts on international & national conferences and workshops (ref: below).
Contributions on HIV/AIDS Prevention and Community Health Development Conferences &
· Conference on Structures of Vulnerability:
Mobilisation and Resistance", “Health and Vulnerability” workshop, Stockholm,
12-14 January 2005. Oral presentation.
Mamo W., Begashaw, B., Wondimu, B. (2005). Holistic approach is
vital in tackling HIV/AIDS epidemic in Africa: an experience from Ethiopia. A Sida/AEHPS supported HIV/AIDS prevention project.
Susanne Selerud (ed), Conference proceedings, pp 172-73, Stockholm MMIV
XV International AIDS Conference. Bangkok, Thailand, 11-16 July
Wamo W. & B. Wondimu (2004). The role of African health professionals in Diaspora
against the spread of HIV/AIDS: Experience & a model from Ethiopia. MedGenMed. 2004 Jul 11; 6 (3): 2004 Jul 11;(1):
· Ist International AIDS Conference in Ethiopia, Addis Ababa, Ethiopia, Nov 7-9, 1999. Chairman of a session
(the role of Diaspora Ethiopians) on and also presented a paper on the role of Diaspora Ethiopians health professionals.
Mamo W., Begashaw, B., Maru, F. Wondimu, B. (1999). The Role of Ethiopian Health
Professionals residing abroad in the battle against HIV/AIDS pandemic in Ethiopia. An Applicable Model?”; Oral
· The Journal
of American Medical association (JAMA). JAMA, Vol. 282 No. 22, December 8, 1999. "Helping their
homeland". On the efforts of AEHHPS in Ethiopia (http://jama.ama-assn.org/cgi/content/extract/282/22/2111).
International Workshop of European partenariat between African communities and health
partners for HIV/AIDS prevention. Stockholm, Sweden, September 28-30, 2000.
Mamo W., Maru, F. Wondimu, B. (2000). Ethiopian Health Professionals in Sweden
in the Battle against HIV/AIDS Pandemic in Ethiopia: An Experience from the Association of Ethiopian Health Professionals
in Sweden (AEHPS);. Oral presentation.
· VIth International workshop of European partenariat between African communities and health partners for HIV/AIDS prevention.
Madrid, Spain January 10-13, 2001.
Wondimu, B & Mamo W (2001). "Cross actions" between sub-Saharan Africa and
Europe on the prevention of HIV/AIDS: An experience of The Association of Ethiopian Health Professionals in Sweden (AEHPS)
in Ethiopia; Oral presentation.
· XIIIth International
Conference on Ethiopian Studies, Kyoto, Japan, December 1997.
Mamo W., Jember, T., Begashaw, B., Moussa, M. (1997). The significant contribution
of community development projects in improving community health. An experience from an Integrated and Holistic Community Development
Project in Ethiopia. In: Ethiopia in Broader Perspectives, Fuku. K, Kurimoto. E and Sheigeta M (Eds.), pp 721-725, ISBN:4-87974-978-8
C3039; Oral presentation.
Countries of Experience
Ethiopia, Russia, Sweden
Computer Skill and Language
user of hardware and software; word processing skills and knowledge of database/ spreadsheet and execution of international
skill: Read, write and speak fluently Amharic (Ethiopian national language), very good English, Swedish and Russian; fair
French and Spanish.
Professional and Public Societies Affiliations (selected)
· International Society for Transgenic
Research (ISTR), member
· International Society for Cryobiology
(ISC), member (http://www.societyforcryobiology.org)
· Scandinavian Federation of Laboratory
Animal Science, member(http://www.med.uib.no/scandlas)
· Swedish Veterinary Association
(SVA), member (http://www.svf.se )
· Association of Ethiopian Health
and health related professionals in Sweden (AEHHPS), board member (http://aehhps.tripod.com)
· People to people anti AIDS organization
(P2P), member (http://www.peoplepeople.org)
association, chairman (http://miaziaalumni.tripod.com)
Built a full operational Transgenic Facility
at Astrazeneca, preclinical R & D, Södertälje, Sweden.
Publications (Refereed Journals)
1) Mamo, W.,
Fröman Gunnar and Müller, H-P. (2000). Protection induced in mice vaccinated with recombinant Collagen-binding protein
(CnBP) and alpha-toxoid against intramammary infection with Staphylococcus aureus. Microbiology & Immunology, 44:5:381-384.
W. (1999). Application of a mouse mastitis model for evaluation of antigen vaccines against Staphylococcus aureus
-induced mastitis. Scand. J. Lab. Anim. Sci. 3:26:124-129.
W., Jonsson, P. and Müller, H-P. (1995). Opsonization of Staphylococcus aureus with a fibronectin-binding protein
antiserum induces protection in mice. Microbiol. Pathogen, 19:49-55.
W., Jonsson, P., Flock, J-I., Müller, H-P. (1995). Induced immunological response of mice vaccinated with fibronectin-binding-proteins
and fibrinogen-binding proteins against Staphylococcus aureus mastitis. Proceedings in The III-rd International Mastitis
Seminar, Tel-Aviv, Israel, May 28-June 1, 1995; SI:86-89.
5) Mamo, W. and Fröman,
G. (1994). In vivo-like antigenic surface properties of S. aureus from bovine mastitis induced upon growth
in milk whey. Microbiology and Immunology, 38:10:801-4.
W., Bodén, M. and Flock, J-I. (1994). Vaccination with Staphylococcus aureus fibrinogen-binding proteins (FbBPs) reduces colonization of S. aureus
in a mouse mastitis model. FEMS Immunol. and Medical Microbiol. 10:47-54.
7) Mamo, W.,
Jonsson, P., Flock, J-I., Lindberg, M., Müller, H. P., Wadström, T. and Nelson, L. (1994). Vaccination
against S. aureus mastitis: Immunological response of mice vaccinated with fibronectin-binding proteins (FnBps) to
challenge with S. aureus. Vaccine, 12:11:988-992.
8) Mamo, W., and Fröman, G. (1994). Adhesion of Staphylococcus aureus
to bovine mammary epithelial cells induced after growth in milk whey. Microbiology and Immunology. 38:305-308.
9) Mamo, W.,
Fröman, G. (1994). Binding of Staphylococcus aureus to extracellular matrix fibronectin and collagen
in relation to wound infection. Wounds, 6 (3):88-93.
10) Mamo, W.,
Lindahl, M., Jonsson, P. (1993). Binding of fibronectin and type II collagen to Staphylococcus aureus: Reduction of binding caused by a periodate-sensitive surface structure induced after growth in milk whey. Wounds.
11) Mamo, W.,
Lindahl, M., and Jonsson, P. (1992). Binding of fibronectin and type II collagen to Staphylococcus aureus from bovine
mastitis: Reduction of binding after growth in milk whey. Microb. Pathogen. 12:443-449.
12) Sandgren, C.H., Mamo,
W., Larsson, I., Lindahl, M. and Björk, I. (1991). A periodate-sensitive
anti-phagocytic surface structure, induced by growth in milk whey on Staphylococcus aureus from bovine mastitis. Microb. Pathogen. 11:211-220.
13) Mamo, W. (1991).
hos S.aureus vid odling i mjölkvassle Svensk Veterinär Tidning, 43:407-409.
14) Mamo, W., Lindahl,
M. and Jonsson, P. (1991). Enhanced virulence of Staphylococcus aureus from bovine mastitis induced by growth in milk whey. Vet. Microbiol. 27:371-384.
15) Mamo, W.,
Sandgren, C. H., Lindahl, M. and Jonsson, P. (1991). Induction of anti-phagocytic surface properties of Staphylococcus
aureus from bovine mastitis by growth in milk whey. J. Vet. Microbiol.B, 38:1-10.
16) Rozgonyi, F., Mamo,
W., Fröman, G., Ljungh, Å., Hjertén, S. and Wadström, T. (1990). Cell surface hydrophobicity and serum-protein
bindings of Methicilline-resistant and-susceptible staphylococcal strains. Zbl. Bakt. Suppl. 21:123-125.
17) Jonsson, P., Mamo,
W. and Lindahl, M. (1989). Surface properties of Staphylococcus aureus related
to virulence in bovine mastitis. In: Proceedings of International Conference on Mastitis, St. Georgen, Austria, 29 May - 2
June, 1989, pp. 135-140.
18) Mamo, W. (1989).
Physical and biochemical surface properties of Gram- positive bacteria in relation to adhesion to bovine mammary cells and
tissues. Rev. Sci. Tech. Off. Int. Epiz., 1:163-176.
19) Jarp, J., Mamo, W. and Johne, B. (1989). Surface properties of Staphylococcus aureus isolated from caprine mastitis. Acta. Vet. Scand. 30:335-339.
20) Mamo, W.,
Fröman, G. and Wadström T. (1988). Interaction of subepithelial connective tissue components with Staphylococcus aureus
and coagulase-negative staphylococci from bovine mastitis. Vet. Microbiol. 18:163-176.
21) Mamo, W., Sundås, A., Fröman, G. and Wadström,
T. (1987). Binding of fibronectin, fibrinogen and type II collagen to streptococci isolated from bovine mastitis. Microb. Pathogen.
22) Mamo, W., Rozgonyi,
F., Hjertén, S. and Wadström, T. (1987). Effect of milk on surface properties of Staphylococcus aureus from bovine
mastitis. FEMS Microbiol. Letts. 48:195-200.
23) Mamo, W.,
Rozgonyi, F., Brown, A., Hjertén, S. and Wadström, T. (1987). Cell-surface hydrophobicity and charge of Staphylococcus
aureus and coagulase-negative staphylococci isolated from bovine mastitis.
J. Appl. Bact. 62:241-249.
24) Mamo, W., & Wadström, T. (1986). Fibronectin,
fibrinogen and type II collagen binding to streptococci isolated from bovine mastitis. In: Proceedings of Symposium on Mastitis
and Hygienic Production of Milk. Marcus Sandholm (ed.). Vammalan Kirjapaino Oy, Vammala, pp. 87-89.
25) Mamo, W., Fröman, G. & Wadström, T. (1986).
Bacterial adhesion as a Virulence factors in bovine mastitis: Possible role of surface hydrophobicity, capsule, fibronectin,
fibrinogen and collagen binding. In: Proceedings of Symposium on Mastitis and Hygienic Production of Milk. Marcus Sandholm
(ed.). Vammalan Kirjapaino Oy, Vammala, pp. 77-87.
1) Mamo, W., Sandgren,
C. H., Jonsson, P., Lindahl, M. and Kenne, L. (1994). Induction of anti-phagocytic carbohydrate surface structure and enhancement
of virulence of S. aureus from bovine mastitis by growth in milk whey. In: Staphylococci and Staphylococcal Infection,
Mölby R. and Flock J-I. (Eds.), Gustav Fischer Verlag, Stuttgart, Jena, New York, pp. 519-523.
2) Mamo, W., Schennings,
T. and Flock, J-I. (1994). Vaccination against S. aureus infection using a fibronectin binding protein. In: Staphylococci
and Staphylococcal Infection, Mölby R. and Flock J-I. (eds.), Gustav Fischer Verlag, Stuttgart, Jena, New York, pp. 555-558.
3) Rozgonyi, F., Ljungh, Å., Mamo, W., Hjertén, S. and Wadström, T. (1990). Bacterial cell surface hydrophobicity. In: Pathogenesis of Wound
and Biomaterial-Associated Infections. Wadström, T., Eliasson, I., Holder, I. and Ljungh, Å. (eds.), Springer Verlag, London,
New York, pp. 233-244.
PhD (VMD) thesis:
(1991). Bovine Mastitis Pathogens: Studies on cell-matrix protein-binding
and induction of potential virulence determinants of Staphylococcus aureus. Swedish University of agricultural Sciences.
Ph.D. thesis, ISBN 91-576-4446-2, Uppsala, Sweden; http://agricola.nal.usda.gov/cgi-bin/Pwebrecon.cgi?Search_Arg=Mamo+wubshet&Search_Code=NAME_&PID=20075&CNT=10&BROWSE=1&HC=1&SID=2).
W. (1983). Laboratory Diagnosis, Specific Prophylaxis and Control of Mass Respiratory Diseases in Cattle. MVSc thesis, Department of Microbiology,
and Virology, Kharkov State Veterinary Academy, Ukraine (http://zoovet.kharkov.ua/eng/index.htm).